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Scientist - II (Strain Engineering)

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Job Description

Perfect Day is on a mission to create a kinder, greener tomorrow using precision fermentation. Leveraging expertise across biology, food innovation, and consumer products, Perfect Day empowers companies to develop, scale, and commercialize next-generation products that satisfy market demands and champion a path towards a more sustainable future.

Reports to: Principal Scientist II

Location: Bangalore

About the Department

_n_th Bio, our enterprise biology platform, is the first of its kind to help partners of all sizes join us in creating a kinder, greener future through precision fermentation. nth Bio is focused on piloting and scaling our technology to partners across industries, including food, agriculture, pharmaceutical, biologics, textile, and personal care to create products in a new, sustainable way.

Position Summary

In this position, you will have responsibilities for developing & implementing strain improvement strategies for producing heterologous proteins, and for engineering strains which will become the workhorse for protein production at commercial scale.

What You Will Do

  • Engineering Strains (Yeast/ Fungus/ E. coli) to express heterologous proteins
  • Design & build plasmids for strain engineering. Transformations into the desired strains.
  • Analysis of transformants & mutants for desired phenotypes & genotypes by cPCR.
  • Routine screening of clones for titer estimation and develop methods for high throughput screening of microbes. Analyze input and output with bioinformatics methods
  • Investigates the feasibility of applying a wide variety of scientific principles and concepts to potential inventions, products and problems. Plans and executes laboratory research.
  • Understand, implement and monitor research studies in a laboratory.

Other functions

  • Perform routine experiments and analyse data to interpret experiment results and report the findings. Give presentations to other members of staff on a regular basis on the progress made.
  • Set up and maintain laboratory equipment and technology, help the team with cataloguing of chemicals, reagents, and consumables.
  • Stay up to date with the latest advances in biotechnology to advance new techniques, products and processes.

What You Bring

We have an opportunity to collaborate to use our unique contributions to create a kinder, greener tomorrow. The dynamic employee we seek is a (Scientist II) with these qualifications.

Education, Experience & Other Requirements

  • M. Sc / M. Tech in molecular biology, Genetics, Biotechnology, Microbial Genetics, or a related discipline.
  • 2 – 4 Years of experience in industrial research is desirable
  • Experience with E. coli or fungal or yeast molecular biology
  • Experience with molecular biology principles required for plasmid construction and design, strain engineering, and gene expression optimization.

Knowledge, Skills & Abilities

  • Bioinformatics skills (Sequence alignments, BLAST, etc.)
  • Sterile working technique
  • Excellent organizational skills
  • Attention to details in experimental operation, lab safety
  • Other desired skills include, excellent communication, ability to handle multiple tasks simultaneously, and good aptitude for data analysis and documentation
  • Strong interpersonal skills, excellent verbal and written communication skills
  • Manage and prioritize multiple tasks, progresses, deadlines

Additional knowledge and skills desired

  • High levels of curiosity and passion to learn new things
  • Demonstrated ability to innovate, troubleshoot, and thrive in a dynamic cross-functional team environment.

Language Skills

Skills that enable a person to communicate orally or in writing in English. These include reading, writing, listening, and speaking.

  • Active Listening
  • Speaking Impactfully
  • Proficient Writing

Perfect Day is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees.

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